Doppler assessment of the effect of chewing Qat on hemodynamics of the common carotid arteries
واصفات البياناتعرض سجل المادة الكامل
Chewing qat has been established to cause cardiovascular and various health problems. The study aims to explore the effects of chewing qat on hemodynamics of the common carotid arteries (CCAs). This is clinically important for quantifying the cerebral perfusion which is a key factor of cerebrovascular diseases. This was a descriptive quantitative study. A total of 200 of healthy non-qat volunteers were investigated with gray scale and Doppler sonography for assessment of common carotid arteries (CCAs) using a 7-10 MHz linear transducers according to a standard carotid sonography protocol. The CCAs hemodynamics, diameters and intima media thickness were assessed. The heart rate and blood pressure were taken on the left arm and measured at 3-5 min interval. The blood flow in CCAs was assessed using the Doppler parameters, peak systolic velocity, end-diastolic velocity, pulsatility index and resistive index. The Doppler parameters were measured before and after chewing qat. SPSS and paired sample t-test was used to analyze the results. A p-value<0.05 was considered to be significant. chewing qat had significantly raised the heart rate and blood pressure (p-value = 0.00 and 0.001, respectively). The blood resistivity and pulsatility of the common carotid arteries were significantly decreased after chewing qat. The peak systolic velocity and maximum end-diastolic velocity were significantly increased after chewing qat (p-values = 0.001 and 0.00, respectively). The diameters and intima media thickness of each CCA were not affected with qat chewing. Chewing qat has significant impact on the hemodynamics of the common carotid arteries, probably as a consequence of vasoconstrictor effect of qat on the blood vessels. This may affect the cerebral perfusion. Further studies are needed on possible morbidity of carotid arteries lesions associated with regular qat chewing.